CLNS1A antibody (AA 160-240)

Catalog No. ABIN7216558

The Rabbit Polyclonal anti-CLNS1A antibody (ABIN7216558) specifically detects CLNS1A in WB, ELISA and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for CLNS1A antibody (AA 160-240) (ABIN7216558)

Target: CLNS1A (Chloride Channel, Nucleotide-Sensitive, 1A (CLNS1A))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLNS1A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-CLNS1A Antibody

Binding Specificity: AA 160-240

Purpose: Rabbit Anti-pICln Polyclonal Antibody

Specificity: PICln Polyclonal Antibody detects endogenous levels of pICln protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human pICln at AA range: 160-240

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300,ELISA 1:2000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CLNS1A

Target: CLNS1A (Chloride Channel, Nucleotide-Sensitive, 1A (CLNS1A))

Alternative Name: pICln

Background: CLNS1A, CLCI, ICLN, Methylosome subunit pICln, Chloride channel, nucleotide sensitive 1A, Chloride conductance regulatory protein ICln, I(Cln), Chloride ion current inducer protein, ClCI, Reticulocyte pIClnT CLNS1A encodes a protein that functions in multiple regulatory pathways. Chloride nucleotide-sensitive channel 1A complexes with numerous cytosolic proteins and performs diverse functions including regulation of small nuclear ribonucleoprotein biosynthesis, platelet activation and cytoskeletal organization. Chloride nucleotide-sensitive channel 1A is also found associated with the plasma membrane where it functions as a chloride current regulator. Pseudogenes of CLNS1A are found on chromosomes 1, 4 and 6. Several transcript variants encoding different isoforms have been found for CLNS1A.

Molecular Weight: 37kD

Gene ID: 1207

UniProt: P54105

Pathways: Ribonucleoprotein Complex Subunit Organization