CHD2 antibody

Catalog No. ABIN7227874

The Rabbit Polyclonal anti-CHD2 antibody (ABIN7227874) specifically detects CHD2 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for CHD2 antibody (ABIN7227874)

Target: CHD2 (Chromodomain Helicase DNA Binding Protein 2 (CHD2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHD2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CHD2 Antibody

Purpose: Rabbit Anti-CHD2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of CHD2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human CHD2 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CHD2

Target: CHD2 (Chromodomain Helicase DNA Binding Protein 2 (CHD2))

Alternative Name: CHD2

Background: Chromodomain-helicase-DNA-binding protein 2, CHD-2, ATP-dependent helicase CHD2CHD2 (Chromodomain Helicase DNA Binding Protein 2) is a Protein Coding gene. Diseases associated with CHD2 include Epileptic Encephalopathy, Childhood-Onset and Chd2 Myoclonic Encephalopathy. Among its related pathways are Chromatin Regulation / Acetylation. The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. CHD genes alter gene expression possibly by modification of chromatin structure thus altering access of the transcriptional apparatus to its chromosomal DNA template. Alternatively spliced transcript variants encoding distinct isoforms have been found for CHD2.

Molecular Weight: 201kD

Gene ID: 1106

UniProt: O14647