CDYL2 antibody (AA 1-80)

Catalog No. ABIN7214140

This Rabbit Polyclonal antibody specifically detects CDYL2 in WB, IHC, ELISA, ICC and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for CDYL2 antibody (AA 1-80) (ABIN7214140)

Target: CDYL2 (Chromodomain Protein, Y-Like 2 (CDYL2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDYL2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Product Details anti-CDYL2 Antibody

Binding Specificity: AA 1-80

Purpose: Rabbit Anti-CDYL2 Polyclonal Antibody

Specificity: CDYL2 Polyclonal Antibody detects endogenous levels of CDYL2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the N-terminal region of human CDYL2 at AA range: 1-80

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ICC 1:200-1:1000,ELISA 1:20000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CDYL2

Target: CDYL2 (Chromodomain Protein, Y-Like 2 (CDYL2))

Alternative Name: CDYL2

Background: CDYL2, Chromodomain Y-like protein 2, CDY-like 2CDY, a gene family expressed exclusively in the testis, localizes to a region of the Y chromosome frequently deleted in infertile males. CDY protein contains two functional domains, an N-terminal chromodomain, possibly functioning in heterochromatin interactions, and also a C-terminal domain which resembles enoyl-CoA-isomerase, a protein involved in fatty acid oxidation. Furthermore, CDY acts as a histone acetyltransferase, with strong preference for histone H4, a process required for the histone to proamine transition in spermatogenesis, consistent with the association with male infertility. Chromodomain Y-like protein (CDYL) is a related ubiquitous nuclear protein expressed at moderate levels in most tissues. The gene encoding for the CDYL protein localizes to chromosome 6p25.1.

Molecular Weight: 56kD

Gene ID: 124359

UniProt: Q8N8U2