CDY1 antibody (AA 210-290)

Catalog No. ABIN7227816

The Rabbit Polyclonal anti-CDY1 antibody is suitable to detect CDY1 in samples from Human. It has been validated for WB and ELISA.

Quick Overview for CDY1 antibody (AA 210-290) (ABIN7227816)

Target: CDY1 (Chromodomain Protein, Y-Linked, 1 (CDY1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDY1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CDY1 Antibody

Binding Specificity: AA 210-290

Purpose: Rabbit Anti-CDY1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of CDY1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human CDY1 protein at AA range: 210-290

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CDY1

Target: CDY1 (Chromodomain Protein, Y-Linked, 1 (CDY1))

Alternative Name: CDY1

Background: Testis-specific chromodomain protein Y 1CDY1 encodes a protein containing a chromodomain and a histone acetyltransferase catalytic domain. Chromodomain proteins are components of heterochromatin-like complexes and can act as gene repressors. This protein is localized to the nucleus of late spermatids where histone hyperacetylation takes place. Histone hyperacetylation is thought to facilitate the transition in which protamines replace histones as the major DNA-packaging protein. The human chromosome Y has two identical copies of this gene within a palindromic region, this record represents the more telomeric copy. Chromosome Y also contains a pair of closely related genes in another more telomeric palindrome as well as several related pseudogenes. Two protein isoforms are encoded by transcript variants of this gene. Additional transcript variants have been described, but their full-length nature has not been determined.

Molecular Weight: 59kD

Gene ID: 253175

UniProt: Q9Y6F8