C16orf61 antibody

Catalog No. ABIN7227960

This Rabbit Polyclonal antibody specifically detects C16orf61 in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for C16orf61 antibody (ABIN7227960)

Target: C16orf61 (Chromosome 16 Open Reading Frame 61 (C16orf61))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C16orf61 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-C16orf61 Antibody

Purpose: Rabbit Anti-CMC2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of CMC2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human CMC2 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for C16orf61

Target: C16orf61 (Chromosome 16 Open Reading Frame 61 (C16orf61))

Alternative Name: CMC2

Background: Calcium-binding mitochondrial carrier protein Aralar2, Citrin, Mitochondrial aspartate glutamate carrier 2, Solute carrier family 25 member 13SLC25A13 is a member of the mitochondrial carrier family. The Solute Carrier Family 25 Member 13 contains four EF-hand Ca(2+) binding motifs in the N-terminal domain, and localizes to mitochondria. The protein catalyzes the exchange of aspartate for glutamate and a proton across the inner mitochondrial membrane, and is stimulated by calcium on the external side of the inner mitochondrial membrane. Mutations in this gene result in citrullinemia, type II. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 74kD

Gene ID: 10165

UniProt: Q9UJS0