TPGS2 antibody

Catalog No. ABIN7230614

The Rabbit Polyclonal anti-TPGS2 antibody (ABIN7230614) specifically detects TPGS2 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for TPGS2 antibody (ABIN7230614)

Target: TPGS2 (C18orf10) (Chromosome 18 Open Reading Frame 10 (C18orf10))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TPGS2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-TPGS2 Antibody

Purpose: Rabbit Anti-PGS2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of PGS2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human PGS2 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for TPGS2

Target: TPGS2 (C18orf10) (Chromosome 18 Open Reading Frame 10 (C18orf10))

Alternative Name: PGS2

Background: Decorin, Bone proteoglycan II, PG-S2, PG40DCN encodes a member of the small leucine-rich proteoglycan family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. Decorin plays a role in collagen fibril assembly. Binding of this protein to multiple cell surface receptors mediates its role in tumor suppression, including a stimulatory effect on autophagy and inflammation and an inhibitory effect on angiogenesis and tumorigenesis. This gene and the related gene biglycan are thought to be the result of a gene duplication. Mutations in this gene are associated with congenital stromal corneal dystrophy in human patients.

Molecular Weight: 39kD

Gene ID: 1634

UniProt: P07585