CMTM8 antibody (Internal Region)

Catalog No. ABIN7226738

This Rabbit Polyclonal antibody specifically detects CMTM8 in ELISA, IHC, WB and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for CMTM8 antibody (Internal Region) (ABIN7226738)

Target: CMTM8 (CKLF-Like MARVEL Transmembrane Domain Containing 8 (CMTM8))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CMTM8 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-CMTM8 Antibody

Binding Specificity: Internal Region

Purpose: Rabbit Anti-CMTM8 Polyclonal Antibody

Specificity: CMTM8 Polyclonal Antibody detects endogenous levels of CMTM8 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human CMTM8

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC: 1:100-1:300,ELISA 1:10000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CMTM8

Target: CMTM8 (CKLF-Like MARVEL Transmembrane Domain Containing 8 (CMTM8))

Alternative Name: CMTM8

Background: CMTM8, CKLFSF8, CKLF-like MARVEL transmembrane domain-containing protein 8, Chemokine-like factor superfamily member 8CMTM8 (CKLF like MARVEL transmembrane domain containing 8) belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and the transmembrane 4 superfamilies. CMTM8 is one of several chemokine-like factor genes located in a cluster on chromosome 3. CMTM8 acts as a tumor suppressor, and plays a role in regulating the migration of tumor cells. The encoded protein is thought to function as a a negative regulator of epidermal growth factor-induced signaling. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molecular Weight: 20kD

Gene ID: 152189

UniProt: Q8IZV2