Claudin 2 antibody (AA 150-230)

Catalog No. ABIN7225806

The Rabbit Polyclonal anti-Claudin 2 antibody is suitable to detect Claudin 2 in samples from Human and Mouse. It has been validated for WB, IHC, ELISA and IF.

Quick Overview for Claudin 2 antibody (AA 150-230) (ABIN7225806)

Target: Claudin 2 (CLDN2)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Claudin 2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-Claudin 2 Antibody

Binding Specificity: AA 150-230

Purpose: Rabbit Anti-Claudin-2 Polyclonal Antibody

Specificity: Claudin-2 Polyclonal Antibody detects endogenous levels of Claudin-2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human Claudin-2 at AA range: 150-230

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:5000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Claudin 2

Target: Claudin 2 (CLDN2)

Alternative Name: Claudin-2

Background: CLDN2, PSEC0059, SP82, Claudin-2, SP82CLDN2 (claudin 2) product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. This protein is expressed in the intestine. Alternatively spliced transcript variants with different 5' untranslated region have been found for CLDN2.

Molecular Weight: 25kD

Gene ID: 9075

UniProt: P57739

Pathways: Hepatitis C