COQ8A antibody (AA 270-350)

Catalog No. ABIN7213894

The Rabbit Polyclonal anti-COQ8A antibody (ABIN7213894) specifically detects COQ8A in WB, ELISA, IF and IHC. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for COQ8A antibody (AA 270-350) (ABIN7213894)

Target: COQ8A (Coenzyme Q8A (COQ8A))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COQ8A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)

Product Details anti-COQ8A Antibody

Binding Specificity: AA 270-350

Purpose: Rabbit Anti-CABC1 Polyclonal Antibody

Specificity: CABC1 Polyclonal Antibody detects endogenous levels of CABC1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human CABC1 at AA range: 270-350

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:10000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for COQ8A

Target: COQ8A (Coenzyme Q8A (COQ8A))

Alternative Name: CABC1

Background: ADCK3, CABC1, PP265, Chaperone activity of bc1 complex-like, mitochondrial, Chaperone-ABC1-like, aarF domain-containing protein kinase 3ADCK3 encodes a mitochondrial protein similar to yeast ABC1, which functions in an electron-transferring membrane protein complex in the respiratory chain. It is not related to the family of ABC transporter proteins. Expression of this gene is induced by the tumor suppressor p53 and in response to DNA damage, and inhibiting its expression partially suppresses p53-induced apoptosis. Alternatively spliced transcript variants have been found, however, their full-length nature has not been determined.

Molecular Weight: 70kD

Gene ID: 56997

UniProt: Q8NI60