CCDC8 antibody

Catalog No. ABIN7227634

The Rabbit Polyclonal anti-CCDC8 antibody (ABIN7227634) specifically detects CCDC8 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for CCDC8 antibody (ABIN7227634)

Target: CCDC8 (Coiled-Coil Domain Containing 8 (CCDC8))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCDC8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CCDC8 Antibody

Purpose: Rabbit Anti-CCDC8 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of CCDC8 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human CCDC8 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CCDC8

Target: CCDC8 (Coiled-Coil Domain Containing 8 (CCDC8))

Alternative Name: CCDC8

Background: Coiled-coil domain-containing protein 8CCDC8 (Coiled-Coil Domain Containing 8) is a Protein Coding gene. Diseases associated with CCDC8 include 3-M Syndrome 3 and 3-M Syndrome, Ccdc8-Related. CCDC8 encodes a coiled-coil domain-containing protein. The encoded protein functions as a cofactor required for p53-mediated apoptosis following DNA damage, and may also play a role in growth through interactions with the cytoskeletal adaptor protein obscurin-like 1. Mutations in CCDC8 are a cause of 3M syndrome-3 (3M3).

Molecular Weight: 59kD

Gene ID: 83987

UniProt: Q9H0W5