COLEC12 antibody

Catalog No. ABIN7228004

The Rabbit Polyclonal anti-COLEC12 antibody is suitable to detect COLEC12 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for COLEC12 antibody (ABIN7228004)

Target: COLEC12 (Collectin Sub-Family Member 12 (COLEC12))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COLEC12 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-COLEC12 Antibody

Purpose: Rabbit Anti-COL12 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of COL12 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human COL12 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for COLEC12

Target: COLEC12 (Collectin Sub-Family Member 12 (COLEC12))

Alternative Name: COL12

Background: Collectin-12, Collectin placenta protein 1, CL-P1, hCL-P1, Nurse cell scavenger receptor 2, Scavenger receptor class A member 4, Scavenger receptor with C-type lectinCOLEC12 encodes a member of the C-lectin family, proteins that possess collagen-like sequences and carbohydrate recognition domains. Collectin Subfamily Member 12 is a scavenger receptor, a cell surface glycoprotein that displays several functions associated with host defense. It can bind to carbohydrate antigens on microorganisms, facilitating their recognition and removal. It also mediates the recognition, internalization, and degradation of oxidatively modified low density lipoprotein by vascular endothelial cells.

Molecular Weight: 81kD

Gene ID: 81035

UniProt: Q5KU26

Pathways: Activation of Innate immune Response