C1S antibody (AA 510-590)

Catalog No. ABIN7224792

The Rabbit Polyclonal anti-C1S antibody (ABIN7224792) specifically detects C1S in WB, IHC, ELISA and IF. The antibody is reactive with Human and Rat samples.

Quick Overview for C1S antibody (AA 510-590) (ABIN7224792)

Target: C1S (Complement Component 1, S Subcomponent (C1S))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C1S antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-C1S Antibody

Binding Specificity: AA 510-590

Purpose: Rabbit Anti-C1s Polyclonal Antibody

Specificity: C1s Polyclonal Antibody detects endogenous levels of C1s protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human C1s at AA range: 510-590

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for C1S

Target: C1S (Complement Component 1, S Subcomponent (C1S))

Alternative Name: C1s

Background: C1S, Complement C1s subcomponent, C1 esterase, Complement component 1 subcomponent sC1S (complement C1s) encodes a serine protease, which is a major constituent of the human complement subcomponent C1. C1s associates with two other complement components C1r and C1q in order to yield the first component of the serum complement system. Defects in this gene are the cause of selective C1s deficiency.

Molecular Weight: 77kD

Gene ID: 716

UniProt: P09871

Pathways: Complement System