CFHR1 antibody

Catalog No. ABIN7228530

This Rabbit Polyclonal antibody specifically detects CFHR1 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for CFHR1 antibody (ABIN7228530)

Target: CFHR1 (Complement Factor H-Related 1 (CFHR1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CFHR1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CFHR1 Antibody

Purpose: FHR1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of FHR1 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human FHR1 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for CFHR1

Target: CFHR1 (Complement Factor H-Related 1 (CFHR1))

Alternative Name: FHR1

Background: Rabbit Anti-FHR1 Polyclonal Antibody,Complement factor H-related protein 1, FHR-1, H factor-like protein 1, H-factor-like 1, H36,CFHR1 encodes Complement Factor H Related 1 belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome.,FHR1

Molecular Weight: observerd band 36kDa

Gene ID: 3078

UniProt: Q03591