CDCP1 antibody (pTyr707)

Catalog No. ABIN7224324

This Rabbit Polyclonal antibody specifically detects CDCP1 in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for CDCP1 antibody (pTyr707) (ABIN7224324)

Target: CDCP1 (CUB Domain Containing Protein 1 (CDCP1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDCP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CDCP1 Antibody

Binding Specificity: pTyr707

Purpose: Rabbit Anti-CD318 (phospho Tyr707) Polyclonal Antibody

Specificity: Phospho-CD318 (Y707) Polyclonal Antibody detects endogenous levels of CD318 protein only when phosphorylated at Y707.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human CD318 Phospho-Tyr707

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:10000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CDCP1

Target: CDCP1 (CUB Domain Containing Protein 1 (CDCP1))

Alternative Name: CD318

Background: CDCP1, TRASK, CUB domain-containing protein 1, Membrane glycoprotein gp140, Subtractive immunization M plus HEp3-associated 135 kDa protein, SIMA135, Transmembrane and associated with src kinases, CD antigen CD318CDCP1 (CUB domain containing protein 1) encodes a transmembrane protein which contains three extracellular CUB domains and acts as a substrate for Src family kinases. The protein plays a role in the tyrosine phosphorylation-dependent regulation of cellular events that are involved in tumor invasion and metastasis. Alternative splicing results in multiple transcript variants of CDCP1.

Molecular Weight: 140,80kD

Gene ID: 64866

UniProt: Q9H5V8