Cullin 4A antibody (AA 590-670)

Catalog No. ABIN7228098

The Rabbit Polyclonal anti-Cullin 4A antibody is suitable to detect Cullin 4A in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for Cullin 4A antibody (AA 590-670) (ABIN7228098)

Target: Cullin 4A (CUL4A)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cullin 4A antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Cullin 4A Antibody

Binding Specificity: AA 590-670

Purpose: Rabbit Anti-CUL4A Polyclonal Antibody

Specificity: The antibody detects endogenous levels of CUL4A protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human CUL4A protein at AA range: 590-670

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Cullin 4A

Target: Cullin 4A (CUL4A)

Alternative Name: CUL4A

Background: Cullin-4A, CUL-4ACUL4A (Cullin 4A) is the ubiquitin ligase component of a multimeric complex involved in the degradation of DNA damage-response proteins. CUL4A is a Protein Coding gene. Diseases associated with CUL4A include Xeroderma Pigmentosum Group E and Xeroderma Pigmentosum, Variant Type. Among its related pathways are Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template and Transcription-Coupled Nucleotide Excision Repair (TC-NER).

Molecular Weight: 83kD

Gene ID: 8451

UniProt: Q13619