Cullin 7 antibody (AA 1570-1650)

Catalog No. ABIN7228102

The Rabbit Polyclonal anti-Cullin 7 antibody is suitable to detect Cullin 7 in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for Cullin 7 antibody (AA 1570-1650) (ABIN7228102)

Target: Cullin 7 (CUL7)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cullin 7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Cullin 7 Antibody

Binding Specificity: AA 1570-1650

Purpose: Rabbit Anti-CUL7 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of CUL7 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human CUL7 protein at AA range: 1570-1650

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Cullin 7

Target: Cullin 7 (CUL7)

Alternative Name: CUL7

Background: Cullin-7, CUL-7The protein encoded by CUL7 (Cullin 7) is a component of an E3 ubiquitin-protein ligase complex. The encoded protein interacts with TP53, CUL9, and FBXW8 proteins. Defects in CUL7 are a cause of 3M syndrome type 1 (3M1). Two transcript variants encoding different isoforms have been found for CUL7. CUL7 is a Protein Coding gene. Diseases associated with CUL7 include 3-M Syndrome 1 and 3-M Syndrome, Cul7-Related. Among its related pathways are Class I MHC mediated antigen processing and presentation and Unfolded Protein Response (UPR).

Molecular Weight: 186kD

Gene ID: 9820

UniProt: Q14999

Pathways: ER-Nucleus Signaling