CNGB3 antibody

Catalog No. ABIN7227976

This Rabbit Polyclonal antibody specifically detects CNGB3 in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for CNGB3 antibody (ABIN7227976)

Target: CNGB3 (Cyclic Nucleotide Gated Channel beta 3 (CNGB3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CNGB3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CNGB3 Antibody

Purpose: Rabbit Anti-CNGB3 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of CNGB3 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human CNGB3 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CNGB3

Target: CNGB3 (Cyclic Nucleotide Gated Channel beta 3 (CNGB3))

Alternative Name: CNGB3

Background: Cyclic nucleotide-gated cation channel beta-3, Cone photoreceptor cGMP-gated channel subunit beta, Cyclic nucleotide-gated cation channel modulatory subunit, Cyclic nucleotide-gated channel beta-3, CNG channel beta-3CNGB3 (Cyclic Nucleotide Gated Channel Beta 3) is a Protein Coding gene. Diseases associated with CNGB3 include Achromatopsia 3 and Stargardt Disease 1. Among its related pathways are Nanog in Mammalian ESC Pluripotency and Activation of cAMP-Dependent PKA. CNGB encodes the beta subunit of a cyclic nucleotide-gated ion channel. The encoded beta subunit appears to play a role in modulation of channel function in cone photoreceptors. This heterotetrameric channel is necessary for sensory transduction, and mutations in this gene have been associated with achromatopsia 3, progressive cone dystrophy, and juvenile macular degeneration, also known as Stargardt Disease.

Molecular Weight: 88kD

Gene ID: 54714

UniProt: Q9NQW8