Cyclin T2 antibody (AA 510-590)
Quick Overview for Cyclin T2 antibody (AA 510-590) (ABIN7227668)
Target
See all Cyclin T2 (CCNT2) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 510-590
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Purpose
- CCNT2 Polyclonal Antibody
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Specificity
- The antibody detects endogenous levels of CCNT2 protein
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Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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Immunogen
- Synthesized peptide derived from part region of human CCNT2 protein at AA range: 510-590
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Cyclin T2 (CCNT2)
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Alternative Name
- CCNT2
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Background
- Rabbit Anti-CCNT2 Polyclonal Antibody,Cyclin-T2, CycT2,The protein encoded by CCNT2 (Cyclin T2) belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin and its kinase partner CDK9 were found to be subunits of the transcription elongation factor p-TEFb. The p-TEFb complex containing this cyclin was reported to interact with, and act as a negative regulator of human immunodeficiency virus type 1 (HIV-1) Tat protein. A pseudogene of this gene is found on chromosome 1. Alternate splicing results in multiple transcript variants.,CCNT2
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Molecular Weight
- observerd band 80kDa
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Gene ID
- 905
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UniProt
- O60583
Target
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