Cyclin-Dependent Kinase 11A (CDK11A) (AA 10-90) antibody

Catalog No. ABIN7216570

The Rabbit Polyclonal anti-Cyclin-Dependent Kinase 11A antibody is suitable to detect Cyclin-Dependent Kinase 11A in samples from Human and Mouse. It has been validated for ELISA, WB, IHC and IF.

Quick Overview for Cyclin-Dependent Kinase 11A (CDK11A) (AA 10-90) antibody (ABIN7216570)

Target: Cyclin-Dependent Kinase 11A (CDK11A)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details

Binding Specificity: AA 10-90

Purpose: Rabbit Anti-PITSLRE Polyclonal Antibody

Specificity: PITSLRE Polyclonal Antibody detects endogenous levels of PITSLRE protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the N-terminal region of human PITSLRE at AA range: 10-90

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details

Target: Cyclin-Dependent Kinase 11A (CDK11A)

Alternative Name: PITSLRE

Background: CDK11B, CDC2L1, CDK11, PITSLREA, PK58, Cyclin-dependent kinase 11B, Cell division cycle 2-like protein kinase 1, CLK-1, Cell division protein kinase 11B, Galactosyltransferase-associated protein kinase p58/GTA, PITSLRE serine/threonine-protCDK11B encodes a member of the serine/threonine protein kinase family. Members of this kinase family are known to be essential for eukaryotic cell cycle control. Due to a segmental duplication, CDK11B shares very high sequence identity with a neighboring gene. These two genes are frequently deleted or altered in neuroblastoma. Cyclin dependent kinase 11B encoded by CDK11B can be cleaved by caspases and may play a role in cell apoptosis. Alternative splicing results in multiple transcript variants.

Molecular Weight: 92kD

Gene ID: 984

UniProt: P21127

Pathways: M Phase