CDC2 / CDK2 antibody (pThr160)

Catalog No. ABIN7213224

This Rabbit Polyclonal antibody specifically detects CDC2 / CDK2 in ELISA, WB and IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for CDC2 / CDK2 antibody (pThr160) (ABIN7213224)

Target: CDC2 / CDK2 (CDC2) (Cyclin-Dependent Kinase A-1 (CDC2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDC2 / CDK2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CDC2 / CDK2 Antibody

Binding Specificity: pThr160

Purpose: Cdk2/Cdc2 (phospho Thr160) Polyclonal Antibody

Specificity: Phospho-Cdk2/Cdc2 (T160) Polyclonal Antibody detects endogenous levels of Cdk2/Cdc2 protein only when phosphorylated at T160.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human Cdk2/Cdc2 Phospho-Thr160

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for CDC2 / CDK2

Target: CDC2 / CDK2 (CDC2) (Cyclin-Dependent Kinase A-1 (CDC2))

Alternative Name: Cdk2/Cdc2

Background: Rabbit Anti-Cdk2/Cdc2 (phospho Thr160) Polyclonal Antibody,CDK2, CDKN2, Cyclin-dependent kinase 2, Cell division protein kinase 2, p33 protein kinase,CDK2 encodes a member of a family of serine/threonine protein kinases that participate in cell cycle regulation. Cyclin dependent kinase 2 is the catalytic subunit of the cyclin-dependent protein kinase complex, which regulates progression through the cell cycle. Activity of this protein is especially critical during the G1 to S phase transition. This protein associates with and regulated by other subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A), and p27Kip1 (CDKN1B). Alternative splicing results in multiple transcript variants.,Cyclin-dependent kinase 2

Molecular Weight: observerd band 34kDa

Gene ID: 1017

UniProt: P24941