CDKN3 antibody (AA 1-80)
Quick Overview for CDKN3 antibody (AA 1-80) (ABIN7218970)
Target
See all CDKN3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1-80
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Purpose
- CDKN3 Polyclonal Antibody
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Specificity
- CDKN3 Polyclonal Antibody detects endogenous levels of CDKN3 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogen
- Synthesized peptide derived from the Internal region of human CDKN3 at AA range: 1-80
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- CDKN3 (Cyclin-Dependent Kinase Inhibitor 3 (CDKN3))
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Alternative Name
- CDKN3
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Background
- Rabbit Anti-CDKN3 Polyclonal Antibody,CDKN3, CDI1, CIP2, KAP, Cyclin-dependent kinase inhibitor 3, CDK2-associated dual-specificity phosphatase, Cyclin-dependent kinase interactor 1, Cyclin-dependent kinase-interacting protein 2, Kinase-associated phosphatase,The cyclin dependent kinase inhibitor 3 encoded by CDKN3 belongs to the dual specificity protein phosphatase family. It was identified as a cyclin-dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. CDKN3 was reported to be deleted, mutated, or overexpressed in several kinds of cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,Cyclin-dependent kinase inhibitor 3
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Molecular Weight
- observerd band 23kDa
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Gene ID
- 1033
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UniProt
- Q16667
Target
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