CDKL3 antibody (AA 260-340)
Quick Overview for CDKL3 antibody (AA 260-340) (ABIN7222996)
Target
See all CDKL3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 260-340
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Purpose
- NKIAMRE Polyclonal Antibody
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Specificity
- NKIAMRE Polyclonal Antibody detects endogenous levels of NKIAMRE protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogen
- Synthesized peptide derived from the Internal region of human NKIAMRE at AA range: 260-340
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- CDKL3 (Cyclin-Dependent Kinase-Like 3 (CDKL3))
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Alternative Name
- NKIAMRE
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Background
- Rabbit Anti-NKIAMRE Polyclonal Antibody,CDKL3, NKIAMRE, Cyclin-dependent kinase-like 3, Serine/threonine-protein kinase NKIAMRE,The protein encoded by CDKL3 (cyclin dependent kinase like 3) is a member of cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. CDKL3 was identified as a gene absent in leukemic patients with chromosome 5q deletion. This loss may be an important determinant of dysmyelopoiesis. Alternative splicing results in multiple transcript variants encoding different isoforms.,Cyclin-dependent kinase-like 3
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Molecular Weight
- observerd band 67kDa
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Gene ID
- 51265
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UniProt
- Q8IVW4
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Pathways
- Cell Division Cycle
Target
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