PPIB antibody (C-Term)

Catalog No. ABIN7218394

The Rabbit Polyclonal anti-PPIB antibody (ABIN7218394) specifically detects PPIB in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for PPIB antibody (C-Term) (ABIN7218394)

Target: PPIB (Cyclophilin B (PPIB))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPIB antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PPIB Antibody

Binding Specificity: C-Term

Purpose: Rabbit Anti-CyPB Polyclonal Antibody

Specificity: CyPB Polyclonal Antibody detects endogenous levels of CyPB protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human CyPB

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PPIB

Target: PPIB (Cyclophilin B (PPIB))

Alternative Name: CyPB

Background: PPIB, CYPB, Peptidyl-prolyl cis-trans isomerase B, PPIase B, CYP-S1, Cyclophilin B, Rotamase B, S-cyclophilin, SCYLPPeptidyl-prolyl cis-trans isomerase B encoded by PPIB is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta.

Molecular Weight: 24kD

Gene ID: 5479

UniProt: P23284