CST11 antibody (AA 50-130)

Catalog No. ABIN7214464

The Rabbit Polyclonal anti-CST11 antibody is suitable to detect CST11 in samples from Human, Mouse and Rat. It has been validated for ELISA and WB.

Quick Overview for CST11 antibody (AA 50-130) (ABIN7214464)

Target: CST11 (Cystatin 11 (CST11))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CST11 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-CST11 Antibody

Binding Specificity: AA 50-130

Purpose: Rabbit Anti-Cystatin 11 Polyclonal Antibody

Specificity: Cystatin 11 Polyclonal Antibody detects endogenous levels of Cystatin 11 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human Cystatin 11 at AA range: 50-130

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:40000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CST11

Target: CST11 (Cystatin 11 (CST11))

Alternative Name: Cystatin 11

Background: CST11, CST8L, Cystatin-11The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes an epididymal-specific protein shown to have antimicrobial activity against E. coli. Alternative splicing yields two variants encoding distinct isoforms.

Molecular Weight: 17kD

Gene ID: 140880

UniProt: Q9H112