CYP3A4 antibody (AA 200-280)

Catalog No. ABIN7224320

The Rabbit Polyclonal anti-CYP3A4 antibody is suitable to detect CYP3A4 in samples from Human. It has been validated for WB, ELISA and IHC (p).

Quick Overview for CYP3A4 antibody (AA 200-280) (ABIN7224320)

Target: CYP3A4 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYP3A4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CYP3A4 Antibody

Binding Specificity: AA 200-280

Purpose: CYP3A43 Polyclonal Antibody

Specificity: CYP3A43 Polyclonal Antibody detects endogenous levels of CYP3A43 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human CYP3A43 at AA range: 200-280

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for CYP3A4

Target: CYP3A4 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4))

Alternative Name: CYP3A43

Background: Rabbit Anti-CYP3A43 Polyclonal Antibody,CYP3A43, Cytochrome P450 3A43,CYP3A43 (cytochrome P450 family 3 subfamily A member 43) encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein has a low level of testosterone hydroxylase activity, and may play a role in aging mechanisms and cancer progression. CYP3A43 is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Alternate splicing results in multiple transcript variants encoding different isoforms.,Cytochrome P450 3A43

Molecular Weight: observerd band 57kDa

Gene ID: 64816

UniProt: Q9HB55

Pathways: Steroid Hormone Biosynthesis