CRLF1 antibody (AA 50-130)

Catalog No. ABIN7228058

This Rabbit Polyclonal antibody specifically detects CRLF1 in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for CRLF1 antibody (AA 50-130) (ABIN7228058)

Target: CRLF1 (Cytokine Receptor-Like Factor 1 (CRLF1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRLF1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CRLF1 Antibody

Binding Specificity: AA 50-130

Purpose: Rabbit Anti-CRLF1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of CRLF1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human CRLF1 protein at AA range: 50-130

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CRLF1

Target: CRLF1 (Cytokine Receptor-Like Factor 1 (CRLF1))

Alternative Name: CRLF1

Background: Cytokine receptor-like factor 1, Cytokine-like factor 1, ZcytoR5CRLF1 (Cytokine Receptor Like Factor 1) is a Protein Coding gene. Diseases associated with CRLF1 include Cold-Induced Sweating Syndrome 1 and Crlf1-Related Cold-Induced Sweating Syndrome Including Crisponi Syndrome. Among its related pathways are Cytokine Signaling in Immune system and Innate Immune System. CRLF1 encodes a member of the cytokine type I receptor family. The protein forms a secreted complex with cardiotrophin-like cytokine factor 1 and acts on cells expressing ciliary neurotrophic factor receptors. The complex can promote survival of neuronal cells. Mutations in CRLF1 result in Crisponi syndrome and cold-induced sweating syndrome.

Molecular Weight: 46kD

Gene ID: 9244

UniProt: O75462