CRLF3 antibody (AA 270-350)

Catalog No. ABIN7228062

This anti-CRLF3 antibody is a Rabbit Polyclonal antibody detecting CRLF3 in WB and ELISA. Suitable for Human and Mouse.

Quick Overview for CRLF3 antibody (AA 270-350) (ABIN7228062)

Target: CRLF3 (Cytokine Receptor-Like Factor 3 (CRLF3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRLF3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CRLF3 Antibody

Binding Specificity: AA 270-350

Purpose: CRLF3 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of CRLF3 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human CRLF3 protein at AA range: 270-350

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for CRLF3

Target: CRLF3 (Cytokine Receptor-Like Factor 3 (CRLF3))

Alternative Name: CRLF3

Background: Rabbit Anti-CRLF3 Polyclonal Antibody,Cytokine receptor-like molecule 9, CREME-9, Cytokine receptor-related protein 4, Type I cytokine receptor-like factor p48,CRLF3 (Cytokine Receptor Like Factor 3) is a Protein Coding gene. CRLF3 encodes a cytokine receptor-like factor that may negatively regulate cell cycle progression at the G0/G1 phase. Studies of the related rat protein suggest that it may regulate neuronal morphology and synaptic vesicle biogenesis. CRLF3 is one of several genes located in the neurofibromatosis type I tumor suppressor region on the q arm of chromosome 17, a region that is subject to microdeletions, duplications, chromosomal breaks and rearrangements. Alternative splicing ofCRLF3 results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 2 and 5.,CRLF3

Molecular Weight: observerd band 48kDa

Gene ID: 51379

UniProt: Q8IUI8

Pathways: p53 Signaling