CYFIP1 antibody (AA 980-1060)

Catalog No. ABIN7228120

This anti-CYFIP1 antibody is a Rabbit Polyclonal antibody detecting CYFIP1 in WB and ELISA. Suitable for Human.

Quick Overview for CYFIP1 antibody (AA 980-1060) (ABIN7228120)

Target: CYFIP1 (Cytoplasmic FMR1 Interacting Protein 1 (CYFIP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYFIP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CYFIP1 Antibody

Binding Specificity: AA 980-1060

Purpose: CYFP1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of CYFP1 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human CYFP1 protein at AA range: 980-1060

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for CYFIP1

Target: CYFIP1 (Cytoplasmic FMR1 Interacting Protein 1 (CYFIP1))

Alternative Name: CYFP1

Background: Rabbit Anti-CYFP1 Polyclonal Antibody,Cytoplasmic FMR1-interacting protein 1 ,Specifically Rac1-associated protein 1, Sra-1,CYFIP1 (Cytoplasmic FMR1 Interacting Protein 1) encodes a protein that regulates cytoskeletal dynamics and protein translation. The encoded protein is a component of the WAVE regulatory complex (WRC), which promotes actin polymerization. This protein also interacts with the Fragile X mental retardation protein (FMRP) and translation initiation factor 4E to inhibit protein translation. A large chromosomal deletion including CYFIP1 is associated with increased risk of schizophrenia and epilepsy in human patients. Reduced expression of CYFIP1 has been observed in various human cancers and the encoded protein may inhibit tumor invasion. CYFIP1 is a Protein Coding gene. Diseases associated with CYFIP1 include Fragile X Syndrome and Schizophrenia. Among its related pathways are RET signaling and Regulation of actin dynamics for phagocytic cup formation.,CYFP1

Molecular Weight: observerd band 137kDa

Gene ID: 23191

UniProt: Q7L576