DOCK11 antibody

Catalog No. ABIN7228270

This Rabbit Polyclonal antibody specifically detects DOCK11 in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for DOCK11 antibody (ABIN7228270)

Target: DOCK11 (Dedicator of Cytokinesis 11 (DOCK11))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DOCK11 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-DOCK11 Antibody

Purpose: Rabbit Anti-DOC11 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of DOC11 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human DOC11 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for DOCK11

Target: DOCK11 (Dedicator of Cytokinesis 11 (DOCK11))

Alternative Name: DOC11

Background: Dedicator of cytokinesis protein 11, Dedicator of cytokinesis protein 11, ACG, Zizimin-2DOCK11 (Dedicator Of Cytokinesis 11) is a Protein Coding gene. Among its related pathways are Response to elevated platelet cytosolic Ca2+ and G-protein signaling_Regulation of CDC42 activity. Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP. Required for marginal zone (MZ) B-cell development, is associated with early bone marrow B-cell development, MZ B-cell formation, MZ B-cell number and marginal metallophilic macrophages morphology. Facilitates filopodia formation through the activation of CDC42.

Molecular Weight: 228kD

Gene ID: 139818

UniProt: Q5JSL3