DLEC1 antibody (AA 1-80)

Catalog No. ABIN7226174

The Rabbit Polyclonal anti-DLEC1 antibody is suitable to detect DLEC1 in samples from Human, Mouse and Rat. It has been validated for ELISA, IHC and IF.

Quick Overview for DLEC1 antibody (AA 1-80) (ABIN7226174)

Target: DLEC1 (Deleted in Lung and Esophageal Cancer 1 (DLEC1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DLEC1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-DLEC1 Antibody

Binding Specificity: AA 1-80

Purpose: Rabbit Anti-DLEC1 Polyclonal Antibody

Specificity: DLEC1 Polyclonal Antibody detects endogenous levels of DLEC1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the N-terminal region of human DLEC1 at AA range: 1-80

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:10000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for DLEC1

Target: DLEC1 (Deleted in Lung and Esophageal Cancer 1 (DLEC1))

Alternative Name: DLEC1

Background: DLEC1, DLC1, Deleted in lung and esophageal cancer protein 1, Deleted in lung cancer protein 1, DLC-1The cytogenetic location of DLEC1 (deleted in lung and esophageal cancer 1) is 3p21. , and it is located in a region that is commonly deleted in a variety of malignancies. Down-regulation of DLEC1 has been observed in several human cancers including lung, esophageal, renal tumors, and head and neck squamous cell carcinoma. In some cases, reduced expression of DLEC1 in tumor cells is a result of aberrant promoter methylation. Several alternatively spliced transcripts have been observed that contain disrupted coding regions and likely encode nonfunctional proteins.

Gene ID: 9940

UniProt: Q9Y238