Desmin antibody (AA 390-470)
Quick Overview for Desmin antibody (AA 390-470) (ABIN7203249)
Target
See all Desmin (DES) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 390-470
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Purpose
- Desmin Polyclonal Antibody
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Specificity
- Desmin Polyclonal Antibody detects endogenous levels of Desmin protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogen
- Synthesized peptide derived from the C-terminal region of human Desmin at AA range: 390-470
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Desmin (DES)
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Alternative Name
- Desmin
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Background
- Rabbit Anti-Desmin Polyclonal Antibody,DES, Desmin,DES encodes a muscle-specific class III intermediate filament. Homopolymers of desmin form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in DES are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.,Desmin
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Gene ID
- 1674
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UniProt
- P17661
Target
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