Desmin antibody (pSer60)

Catalog No. ABIN7220022

The Rabbit Polyclonal anti-Desmin antibody has been validated for ELISA and IHC (p). It is suitable to detect Desmin in samples from Human, Rat and Mouse.

Quick Overview for Desmin antibody (pSer60) (ABIN7220022)

Target: Desmin (DES)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Desmin antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Desmin Antibody

Binding Specificity: pSer60

Purpose: Desmin (phospho Ser60) Polyclonal Antibody

Specificity: Phospho-Desmin (S60) Polyclonal Antibody detects endogenous levels of Desmin protein only when phosphorylated at S60.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human Desmin Phospho-Ser60

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for Desmin

Target: Desmin (DES)

Alternative Name: Desmin

Background: Rabbit Anti-Desmin (phospho Ser60) Polyclonal Antibody,DES, Desmin,DES encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.,Desmin

Gene ID: 1674

UniProt: P17661