Desmoglein 4 antibody

Catalog No. ABIN7228310

The Rabbit Polyclonal anti-Desmoglein 4 antibody (ABIN7228310) specifically detects Desmoglein 4 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Desmoglein 4 antibody (ABIN7228310)

Target: Desmoglein 4 (DSG4)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Desmoglein 4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Desmoglein 4 Antibody

Purpose: Rabbit Anti-DSG4 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of DSG4 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human DSG4 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Desmoglein 4

Target: Desmoglein 4 (DSG4)

Alternative Name: DSG4

Background: Desmoglein-4, Cadherin family member 13DSG4 (Desmoglein 4) is a Protein Coding gene. Diseases associated with DSG4 include Hypotrichosis 6 and Monilethrix. Among its related pathways are Keratinization and Developmental Biology. DSG4 encodes a member of the desmoglein subgroup of desmosomal cadherins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a transmembrane component of desmosomes and may play a role in cell-cell adhesion in epithelial cells. Mutations in the gene are associated with localized autosomal recessive hypotrichosis and monilethrix, characterized by impaired hair growth.

Molecular Weight: 114kD

Gene ID: 147409

UniProt: Q86SJ6