DUSL2 antibody (AA 390-470)

Catalog No. ABIN7223336

This anti-DUSL2 antibody is a Rabbit Polyclonal antibody detecting DUSL2 in WB, ELISA and IHC (p). Suitable for Human and Mouse.

Quick Overview for DUSL2 antibody (AA 390-470) (ABIN7223336)

Target: DUSL2 (DUS2L) (Dihydrouridine Synthase 2-Like (DUS2L))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DUSL2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-DUSL2 Antibody

Binding Specificity: AA 390-470

Purpose: DUS2L Polyclonal Antibody

Specificity: DUS2L Polyclonal Antibody detects endogenous levels of DUS2L protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the C-terminal region of human DUS2L at AA range: 390-470

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for DUSL2

Target: DUSL2 (DUS2L) (Dihydrouridine Synthase 2-Like (DUS2L))

Alternative Name: DUS2L

Background: Rabbit Anti-DUS2L Polyclonal Antibody,DUS2L, DUS2, tRNA-dihydrouridine(20) synthase [NAD(P)+]-like, Up-regulated in lung cancer protein 8, URLC8, tRNA-dihydrouridine synthase 2-like, hDUS2,DUS2 (dihydrouridine synthase 2) encodes a cytoplasmic protein that catalyzes the conversion of uridine residues to dihydrouridine in the D-loop of tRNA. The resulting modified bases confer enhanced regional flexibility to tRNA. The encoded protein may increase the rate of translation by inhibiting an interferon-induced protein kinase. DUS2 has been implicated in pulmonary carcinogenesis. Alternatively spliced transcript variants have been described for DUS2.,tRNA-dihydrouridine(20) synthase [NAD(P)+]-like

Molecular Weight: observerd band 55kDa

Gene ID: 54920

UniProt: Q9NX74