DLG3 antibody

Catalog No. ABIN7228236

This Rabbit Polyclonal antibody specifically detects DLG3 in WB and ELISA. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for DLG3 antibody (ABIN7228236)

Target: DLG3 (Discs, Large Homolog 3 (DLG3))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DLG3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-DLG3 Antibody

Purpose: Rabbit Anti-DLG3 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of DLG3 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human DLG3 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for DLG3

Target: DLG3 (Discs, Large Homolog 3 (DLG3))

Alternative Name: DLG3

Background: Disks large homolog 3, Neuroendocrine-DLG, Synapse-associated protein 102, SAP-102, SAP102DLG3 (Discs Large MAGUK Scaffold Protein 3) is a Protein Coding gene. Diseases associated with DLG3 include X-Linked Non-Specific Intellectual Disability and Non-Syndromic Intellectual Disability. Among its related pathways are PI3K-Akt signaling pathway and Protein-protein interactions at synapses. DLG3 encodes a member of the membrane-associated guanylate kinase protein family. The encoded protein may play a role in clustering of NMDA receptors at excitatory synapses. It may also negatively regulate cell proliferation through interaction with the C-terminal region of the adenomatosis polyposis coli tumor suppressor protein. Mutations in this gene have been associated with X-linked cognitive disability. Alternatively spliced transcript variants have been described.

Molecular Weight: 89kD

Gene ID: 1741

UniProt: Q92796