DVL1 antibody

Catalog No. ABIN7228320

This Rabbit Polyclonal antibody specifically detects DVL1 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for DVL1 antibody (ABIN7228320)

Target: DVL1 (Dishevelled Segment Polarity Protein 1 (DVL1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DVL1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-DVL1 Antibody

Purpose: DVL1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of DVL1 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human DVL1 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for DVL1

Target: DVL1 (Dishevelled Segment Polarity Protein 1 (DVL1))

Alternative Name: DVL1

Background: Rabbit Anti-DVL1 Polyclonal Antibody,Segment polarity protein dishevelled homolog DVL-1, Dishevelled-1, DSH homolog 1,DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development.,DVL1

Molecular Weight: observerd band 76kDa

Gene ID: 1855

UniProt: O14640

Pathways: WNT Signaling, Synaptic Membrane, Skeletal Muscle Fiber Development