DOK5 antibody (AA 70-150)

Catalog No. ABIN7223528

This Rabbit Polyclonal antibody specifically detects DOK5 in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for DOK5 antibody (AA 70-150) (ABIN7223528)

Target: DOK5 (Docking Protein 5 (DOK5))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DOK5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-DOK5 Antibody

Binding Specificity: AA 70-150

Purpose: Dok-5 Polyclonal Antibody

Specificity: Dok-5 Polyclonal Antibody detects endogenous levels of Dok-5 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human Dok-5 at AA range: 70-150

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for DOK5

Target: DOK5 (Docking Protein 5 (DOK5))

Alternative Name: Dok-5

Background: Rabbit Anti-Dok-5 Polyclonal Antibody,DOK5, C20orf180, Docking protein 5, Downstream of tyrosine kinase 5, Insulin receptor substrate 6, IRS-6, IRS6,The protein encoded by DOK5 (docking protein 5) is a member of the DOK family of membrane proteins, which are adapter proteins involved in signal transduction. The encoded protein interacts with phosphorylated receptor tyrosine kinases to mediate neurite outgrowth and activation of the MAP kinase pathway. Unlike other DOK family proteins, this protein does not interact with RASGAP. This protein is up-regulated in patients with systemic sclerosis and is associated with fibrosis induced by insulin-like growth factor binding protein 5. Alternative splicing of DOK5 results in multiple transcript variants.,Docking protein 5

Molecular Weight: observerd band 36kDa

Gene ID: 55816

UniProt: Q9P104