CP4F3 antibody (AA 400-480)

Catalog No. ABIN7228034

This Rabbit Polyclonal antibody specifically detects CP4F3 in ELISA and WB. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for CP4F3 antibody (AA 400-480) (ABIN7228034)

Target: CP4F3 (LOC106592262) (Docosahexaenoic Acid omega-Hydroxylase CYP4F3-Like (LOC106592262))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CP4F3 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-CP4F3 Antibody

Binding Specificity: AA 400-480

Purpose: Rabbit Anti-CP4F3 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of CP4F3 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human CP4F3 protein at AA range: 400-480

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for CP4F3

Target: CP4F3 (LOC106592262) (Docosahexaenoic Acid omega-Hydroxylase CYP4F3-Like (LOC106592262))

Alternative Name: CP4F3

Background: 20-hydroxyeicosatetraenoic acid synthase, 20-HETE synthase, CYPIVF3, Cytochrome P450 4F3, Cytochrome P450-LTB-omega, Leukotriene-B(4) 20-monooxygenase 2, Leukotriene-B(4) omega-hydroxylase 2CYP4F3 encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. The enzyme starts the process of inactivating and degrading leukotriene B4, a potent mediator of inflammation. CYP4F3 is part of a cluster of cytochrome P450 genes on chromosome 19. Another member of this family, CYP4F8, is approximately 18 kb away. Three transcript variants encoding two different isoforms have been found for CYP4F3.

Molecular Weight: 57kD

Gene ID: 4051

UniProt: Q08477