DSCAM antibody

Catalog No. ABIN7228304

The Rabbit Polyclonal anti-DSCAM antibody is suitable to detect DSCAM in samples from Human, Mouse and Rat. It has been validated for ELISA and WB.

Quick Overview for DSCAM antibody (ABIN7228304)

Target: DSCAM (Down Syndrome Cell Adhesion Molecule (DSCAM))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DSCAM antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-DSCAM Antibody

Purpose: Rabbit Anti-DSCAM Polyclonal Antibody

Specificity: The antibody detects endogenous levels of DSCAM protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human DSCAM protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for DSCAM

Target: DSCAM (Down Syndrome Cell Adhesion Molecule (DSCAM))

Alternative Name: DSCAM

Background: Down syndrome cell adhesion molecule, CHD2DSCAM is a member of the immunoglobulin superfamily of cell adhesion molecules (Ig-CAMs) and is involved in human central and peripheral nervous system development. DSCAM is a candidate for Down syndrome and congenital heart disease (DSCHD). A gene encoding a similar Ig-CAM protein is located on chromosome 11. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. DSCAM (DS Cell Adhesion Molecule) is a Protein Coding gene. Diseases associated with DSCAM include Down Syndrome-Related Congenital Heart Disease and Down Syndrome. Among its related pathways are Cell junction organization and Guidance Cues and Growth Cone Motility. An important paralog of this gene is DSCAML1.

Molecular Weight: 221kD

Gene ID: 1826

UniProt: O60469

Pathways: Regulation of Cell Size