DYRK3 antibody (AA 1-80)
Quick Overview for DYRK3 antibody (AA 1-80) (ABIN7228332)
Target
See all DYRK3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1-80
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Purpose
- DYRK3 Polyclonal Antibody
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Specificity
- The antibody detects endogenous levels of DYRK3 protein
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Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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Immunogen
- Synthesized peptide derived from part region of human DYRK3 protein at AA range: 1-80
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- DYRK3 (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 3 (DYRK3))
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Alternative Name
- DYRK3
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Background
- Rabbit Anti-DYRK3 Polyclonal Antibody,Dual specificity tyrosine-phosphorylation-regulated kinase 3, Regulatory erythroid kinase, EDK,DYRK3 product belongs to the DYRK family of dual-specificity protein kinases that catalyze autophosphorylation on serine/threonine and tyrosine residues. The members of this family share structural similarity, however, differ in their substrate specificity, suggesting their involvement in different cellular functions. The encoded protein has been shown to autophosphorylate on tyrosine residue and catalyze phosphorylation of histones H3 and H2B in vitro. Alternatively spliced transcript variants encoding different isoforms have been identified.,DYRK3
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Molecular Weight
- observerd band 64kDa
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Gene ID
- 8444
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UniProt
- O43781
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Pathways
- Negative Regulation of Hormone Secretion, Regulation of Lipid Metabolism by PPARalpha
Target
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