DNMBP antibody

Catalog No. ABIN7228266

The Rabbit Polyclonal anti-DNMBP antibody (ABIN7228266) specifically detects DNMBP in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for DNMBP antibody (ABIN7228266)

Target: DNMBP (Dynamin Binding Protein (DNMBP))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DNMBP antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-DNMBP Antibody

Purpose: Rabbit Anti-DNMBP Polyclonal Antibody

Specificity: The antibody detects endogenous levels of DNMBP protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human DNMBP protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for DNMBP

Target: DNMBP (Dynamin Binding Protein (DNMBP))

Alternative Name: DNMBP

Background: Dynamin-binding protein, Scaffold protein TubaDNMBP gene encodes a protein belonging to the guanine nucleotide exchange factor family, and which regulates the configuration of cell junctions. It contains multiple binding sites for dynamin and thus links dynamin to actin regulatory proteins. Polymorphisms in this gene have been linked to Alzheimer's disease in some populations, though there are conflicting reports of such linkages in other populations. Alternative splicing results in multiple transcript variants.

Molecular Weight: 173kD

Gene ID: 23268

UniProt: Q6XZF7