E2F3 antibody (acLys168)

Catalog No. ABIN7226784

The Rabbit Polyclonal anti-E2F3 antibody has been validated for WB and ELISA. It is suitable to detect E2F3 in samples from Human, Mouse and Rat.

Quick Overview for E2F3 antibody (acLys168) (ABIN7226784)

Target: E2F3

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This E2F3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-E2F3 Antibody

Binding Specificity: acLys168

Purpose: E2F-3 (Acetyl-Lys168) Polyclonal Antibody

Specificity: The antibody detects endogenous E2F-3 (Acetyl-Lys168) protein.

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthetic peptide from human protein at AA range: 130-200

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:10000), ELISA (1:10000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for E2F3

Target: E2F3

Alternative Name: E2F-3

Background: Rabbit Anti-E2F-3 (Acetyl-Lys168) Polyclonal Antibody,E2F3 KIAA0075,E2F3 (E2F transcription factor 3) encodes a member of a small family of transcription factors that function through binding of DP interaction partner proteins. The encoded protein recognizes a specific sequence motif in DNA and interacts directly with the retinoblastoma protein (pRB) to regulate the expression of genes involved in the cell cycle. Altered copy number and activity of this gene have been observed in a number of human cancers. There are pseudogenes for this gene on chromosomes 2 and 17. Alternative splicing results in multiple transcript variants.,E2F transcription factor 3

Molecular Weight: observerd band 50kDa

Gene ID: 1871

UniProt: O00716