EBF3 antibody (AA 50-130)

Catalog No. ABIN7228002

The Rabbit Polyclonal anti-EBF3 antibody (ABIN7228002) specifically detects EBF3 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for EBF3 antibody (AA 50-130) (ABIN7228002)

Target: EBF3 (Early B-Cell Factor 3 (EBF3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EBF3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-EBF3 Antibody

Binding Specificity: AA 50-130

Purpose: Rabbit Anti-COE3 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of COE3 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human COE3 protein at AA range: 50-130

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for EBF3

Target: EBF3 (Early B-Cell Factor 3 (EBF3))

Alternative Name: COE3

Background: Transcription factor COE3, Early B-cell factor 3, EBF-3, O/E-2, OE-2EBF3 (Early B-Cell Factor 3) encodes a member of the early B-cell factor (EBF) family of DNA binding transcription factors. EBF proteins are involved in B-cell differentiation, bone development and neurogenesis, and may also function as tumor suppressors. The encoded protein inhibits cell survival through the regulation of genes involved in cell cycle arrest and apoptosis, and aberrant methylation or deletion of EBF3 may play a role in multiple malignancies including glioblastoma multiforme and gastric carcinoma.

Molecular Weight: 65kD

Gene ID: 253738

UniProt: Q9H4W6