Ectodysplasin A antibody (Internal Region)

Catalog No. ABIN7226662

The Rabbit Polyclonal anti-Ectodysplasin A antibody (ABIN7226662) specifically detects Ectodysplasin A in WB, ELISA, IHC and IF. The antibody is reactive with Human and Mouse samples.

Quick Overview for Ectodysplasin A antibody (Internal Region) (ABIN7226662)

Target: Ectodysplasin A (EDA)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ectodysplasin A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-Ectodysplasin A Antibody

Binding Specificity: Internal Region

Purpose: Rabbit Anti-EDA Polyclonal Antibody

Specificity: EDA Polyclonal Antibody detects endogenous levels of EDA protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human EDA

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC: 1:100-1:300,ELISA 1:10000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Ectodysplasin A

Target: Ectodysplasin A (EDA)

Alternative Name: EDA

Background: EDA, ED1, EDA2, Ectodysplasin-A, Ectodermal dysplasia protein, EDA proteinThe protein encoded by EDA (ectodysplasin A) is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in EDA are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for EDA.

Molecular Weight: 42kD

Gene ID: 1896

UniProt: Q92838

Pathways: Tube Formation