EDAR antibody (AA 50-130)

Catalog No. ABIN7228346

This Rabbit Polyclonal antibody specifically detects EDAR in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for EDAR antibody (AA 50-130) (ABIN7228346)

Target: EDAR (Ectodysplasin A Receptor (EDAR))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EDAR antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-EDAR Antibody

Binding Specificity: AA 50-130

Purpose: Rabbit Anti-EDAR Polyclonal Antibody

Specificity: The antibody detects endogenous levels of EDAR protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human EDAR protein at AA range: 50-130

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for EDAR

Target: EDAR (Ectodysplasin A Receptor (EDAR))

Alternative Name: EDAR

Background: Tumor necrosis factor receptor superfamily member EDAR, Anhidrotic ectodysplasin receptor 1, Downless homolog, EDA-A1 receptor, Ectodermal dysplasia receptor, Ectodysplasin-A receptorEDAR encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in EDAR result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia.

Molecular Weight: 49kD

Gene ID: 10913

UniProt: Q9UNE0

Pathways: Tube Formation, Ubiquitin Proteasome Pathway