ECE2 antibody

Catalog No. ABIN7228344

The Rabbit Polyclonal anti-ECE2 antibody is suitable to detect ECE2 in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for ECE2 antibody (ABIN7228344)

Target: ECE2 (Endothelin Converting Enzyme 2 (ECE2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ECE2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ECE2 Antibody

Purpose: ECE2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of ECE2 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human ECE2 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for ECE2

Target: ECE2 (Endothelin Converting Enzyme 2 (ECE2))

Alternative Name: ECE2

Background: Rabbit Anti-ECE2 Polyclonal Antibody,Endothelin-converting enzyme 2,ECE2 (Endothelin Converting Enzyme 2) is a Protein Coding gene. Among its related pathways are A-beta Pathways: uptake and Degradation and Peptide ligand-binding receptors. GO annotations related to this gene include methyltransferase activity and metalloendopeptidase activity. An important paralog of this gene is ECE1. Converts big endothelin-1 to endothelin-1. Also involved in the processing of various neuroendocrine peptides, including neurotensin, angiotensin I, substance P, proenkephalin-derived peptides, and prodynorphin-derived peptides. May limit beta-amyloid peptide accumulation in brain. May also have methyltransferase activity.,ECE2

Molecular Weight: observerd band 97kDa

Gene ID: 9718

UniProt: O60344

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling