ECE1 antibody

Catalog No. ABIN7228342

This Rabbit Polyclonal antibody specifically detects ECE1 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for ECE1 antibody (ABIN7228342)

Target: ECE1 (Endothelin-Converting Enzyme 1 (ECE1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ECE1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ECE1 Antibody

Purpose: Rabbit Anti-ECE1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of ECE1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human ECE1 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ECE1

Target: ECE1 (Endothelin-Converting Enzyme 1 (ECE1))

Alternative Name: ECE1

Background: The protein encoded by ECE1 is involved in proteolytic processing of endothelin precursors to biologically active peptides. Mutations in ECE1 are associated with Hirschsprung disease, cardiac defects and autonomic dysfunction. Alternatively spliced transcript variants encoding different isoforms have been noted for ECE1.

Molecular Weight: 84kD

Gene ID: 1889

UniProt: P42892

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling