ELMO1 antibody (N-Term)

Catalog No. ABIN7217612

The Rabbit Polyclonal anti-ELMO1 antibody is suitable to detect ELMO1 in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for ELMO1 antibody (N-Term) (ABIN7217612)

Target: ELMO1 (Engulfment and Cell Motility 1 (ELMO1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ELMO1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ELMO1 Antibody

Binding Specificity: N-Term

Purpose: Rabbit Anti-Elmo1 Polyclonal Antibody

Specificity: Elmo1 Polyclonal Antibody detects endogenous levels of Elmo1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the N-terminal region of human Elmo1

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ELMO1

Target: ELMO1 (Engulfment and Cell Motility 1 (ELMO1))

Alternative Name: Elmo1

Background: ELMO1, KIAA0281, Engulfment and cell motility protein 1, Protein ced-12 homologELMO1 encodes a member of the engulfment and cell motility protein family. Engulfment and cell motility protein 1 interact with dedicator of cytokinesis proteins to promote phagocytosis and cell migration. Increased expression of this gene and dedicator of cytokinesis 1 may promote glioma cell invasion, and single nucleotide polymorphisms in this gene may be associated with diabetic nephropathy. Alternative splicing results in multiple transcript variants.

Molecular Weight: 83kD

Gene ID: 9844

UniProt: Q92556