EPH Receptor A2 antibody (AA 100-180)
Quick Overview for EPH Receptor A2 antibody (AA 100-180) (ABIN7220178)
Target
See all EPH Receptor A2 (EPHA2) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 100-180
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Purpose
- EphA2 Polyclonal Antibody
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Specificity
- EphA2 Polyclonal Antibody detects endogenous levels of EphA2 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogen
- Synthesized peptide derived from the N-terminal region of human EphA2 at AA range: 100-180
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- EPH Receptor A2 (EPHA2)
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Alternative Name
- EphA2
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Background
- Rabbit Anti-EphA2 Polyclonal Antibody,EPHA2, ECK, Ephrin type-A receptor 2, Epithelial cell kinase, Tyrosine-protein kinase receptor ECK,EPHA2 belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Mutations in this gene are the cause of certain genetically-related cataract disorders.,Ephrin type-A receptor 2
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Molecular Weight
- observerd band 105kDa
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Gene ID
- 1969
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UniProt
- P29317
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Pathways
- RTK Signaling
Target
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