Ephrin A2 antibody (Cleaved-Asn188)

Catalog No. ABIN7212474

This Rabbit Polyclonal antibody specifically detects Ephrin A2 in WB and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for Ephrin A2 antibody (Cleaved-Asn188) (ABIN7212474)

Target: Ephrin A2 (EFNA2)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ephrin A2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Ephrin A2 Antibody

Binding Specificity: AA 110-190, Cleaved-Asn188

Purpose: Cleaved-Ephrin-A2 (N188) Polyclonal Antibody

Specificity: Cleaved-Ephrin-A2 (N188) Polyclonal Antibody detects endogenous levels of fragment of activated Ephrin-A2 protein resulting from cleavage adjacent to N188.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the C-terminal region of human Ephrin-A2 at AA range: 110-190

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:20000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for Ephrin A2

Target: Ephrin A2 (EFNA2)

Alternative Name: Ephrin-A2

Background: Rabbit Anti-Cleaved-Ephrin-A2 (N188) Polyclonal Antibody,EFNA2, EPLG6, LERK6, Ephrin-A2, EPH-related receptor tyrosine kinase ligand 6, LERK-6, HEK7 ligand, HEK7-L,EFNA2 encodes a member of the ephrin family. Ephrin A2 is composed of a signal sequence, a receptor-binding region, a spacer region, and a hydrophobic region. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. Posttranslational modifications determine whether ephrin A2 localizes to the nucleus or the cytoplasm.,Ephrin-A2

Molecular Weight: observerd band 21kDa

Gene ID: 1943

UniProt: O43921